SAS/R code of MSD method for comparing dis­so­lution [Dissolution / BCS / IVIVC]

posted by Olga – Belarus, 2018-04-21 07:01 (1281 d 22:24 ago) – Posting: # 18712
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Hi, Shuanghe,
Thanks a lot for R code.
It's very helpful!

I have a question about max MRD.

You calculate it from vector m_dg    <- cbind(rep(dg, p))
where dg is same positive value (often 10% - max inter-batch difference).
I wonder -why only positive value?

I suppose, max inter-batch difference is absolute value, and may be positive or negative, or it is my mistake?

I modeled vector m_dg like m_dg <- c(10,-10....), of course, results were various.

Thanks in advance!

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