Zero Sample Preparation [Bioanalytics]

posted by Obinoscopy  – USA, 2018-04-15 04:19 (1995 d 12:19 ago) – Posting: # 18682
Views: 3,571

Hi guys,

How is the zero sample prepared? I know the blank sample is a biological matrix without the analyte and its internal standard. I also know the non zero samples are biological matrix spiked with a particular concentration of the analyte and same concentration of the internal standard.

The zero sample is a biological matrix spiked with the internal standard only. My question is this: What is the actual concentration of the internal standard that should be used to prepare the zero sample?

Obinoscopy

Scopy

Complete thread:

UA Flag
Activity
 Admin contact
22,763 posts in 4,775 threads, 1,628 registered users;
9 visitors (0 registered, 9 guests [including 1 identified bots]).
Forum time: 16:38 CEST (Europe/Vienna)

Restlessness is discontent –
and discontent is the first necessity of progress.
Show me a thoroughly satisfied man 
and I will show you a failure.    Thomas Alva Edison

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5