f2 comparison [Dissolution / BCS / IVIVC]

posted by wienui  – Germany/Oman, 2018-04-10 19:39 (1996 d 03:50 ago) – Posting: # 18663
Views: 4,306

(edited by wienui on 2018-04-11 06:11)

Hi John,
Yes you need to calculate the f2 (as you cann't prove the release at 15 min was ≥ 85%.) for the above given 3 dissolution time points and don't include anymore time points.
What about the CV% or RSD% for the 10min and the other time points? otherwise bootstrapping is recommended.
Best regards,

Edit: Full quote removed. Please delete everything from the text of the original poster which is not necessary in understanding your answer; see also this post #5[Helmut]


Complete thread:

UA Flag
 Admin contact
22,761 posts in 4,775 threads, 1,628 registered users;
19 visitors (0 registered, 19 guests [including 6 identified bots]).
Forum time: 23:29 CEST (Europe/Vienna)

Medical researches can be divided into two sorts:
those who think that meta is better and those
who believe that pooling is fooling.    Stephen Senn

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz