f2 comparison [Dissolution / BCS / IVIVC]

posted by wienui  – Germany/Oman, 2018-04-10 19:39 (2000 d 13:31 ago) – Posting: # 18663
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(edited by wienui on 2018-04-11 06:11)

Hi John,
Yes you need to calculate the f2 (as you cann't prove the release at 15 min was ≥ 85%.) for the above given 3 dissolution time points and don't include anymore time points.
What about the CV% or RSD% for the 10min and the other time points? otherwise bootstrapping is recommended.
Best regards,

Edit: Full quote removed. Please delete everything from the text of the original poster which is not necessary in understanding your answer; see also this post #5[Helmut]


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