f2 comparison [Dissolution / BCS / IVIVC]

posted by wienui  – Germany, Oman, 2018-04-10 17:39 (1337 d 17:21 ago) – Posting: # 18663
Views: 3,846

(edited by wienui on 2018-04-11 06:11)

Hi John,
Yes you need to calculate the f2 (as you cann't prove the release at 15 min was ≥ 85%.) for the above given 3 dissolution time points and don't include anymore time points.
What about the CV% or RSD% for the 10min and the other time points? otherwise bootstrapping is recommended.
Best regards,
Osama


Edit: Full quote removed. Please delete everything from the text of the original poster which is not necessary in understanding your answer; see also this post #5[Helmut]

Cheers,
Osama

Complete thread:

Activity
 Admin contact
21,788 posts in 4,557 threads, 1,548 registered users;
online 5 (0 registered, 5 guests [including 4 identified bots]).
Forum time: Wednesday 10:01 CET (Europe/Vienna)

There is no adequate defense, except stupidity,
against the impact of a new idea.    Percy Williams Bridgman

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5