Bioequivalence and Bioavailability Forum • Power R WinNonLin

Power R WinNonLin [Power / Sample Size]

posted by pjs – India, 2018-03-23 11:41 (1834 d 18:23 ago) – Posting: # 18589
Views: 7,116

Hi All,

Below is the power reported for the assumed parameters with different software.

❝ From the research 2x2x2 (34 - balanced) for power estimation the following results are taken: β=0.20, α=0.05, CV = 0.32, PE = 0.92

❝

❝ FARTSSIE17: 55%

❝ R: 55%

❝ WinNonLin: Power_80_20: 89%

Can you pls guide for FARTSSIE and R which method for power estimation is being used.

Currently i am cross verifying power value with the published paper of the potvin for two stage. They had calculated power with modification of Hauschke et al. For example if i take N=12, CV=40% and ratio 95% power by method C is reported to be 0.7505. For the same parameters power by FARTSSIE is -24.19%.

Regards
Pjs

Complete thread:

Power R WinNonLin Yura 2018-01-23 15:02 [Power / Sample Size]
- Power R WinNonLin d_labes 2018-01-23 15:25
  - Power_TOST in PHX/WNL 6.4+ Helmut 2018-01-23 16:05
    - Power_TOST in PHX/WNL 6.4+ d_labes 2018-01-23 16:54
      - Power_TOST in PHX/WNL 6.4+ Helmut 2018-01-23 17:25
    - Power_TOST in PHX/WNL 6.4+ Yura 2018-01-23 21:55
- Power R WinNonLinpjs 2018-03-23 10:41
  - Power of two stage design d_labes 2018-03-23 17:02
  - Power2Stage / power.2stage() Helmut 2018-03-24 15:49