Postural restriction [Design Issues]

posted by lakshmiprasad – India, 2018-03-17 09:20 (1359 d 15:35 ago) – Posting: # 18563
Views: 5,140

Hi,

Good afternoon to all,

Please any one help to me on below mentioned.

I would like to know about the postural restriction of subjects after dosing. I have doubt on supine postural restriction.

Ex:

Generally Whenever i was wrote the protocol, based on product prescribed information i will make it the postural restriction 02 hours or 04 hours (based on the molecule Tmax i.e., 2, 4) supine position in case molecule will be created the somnolence.

Now my doubt is if molecule Tmax is 6 or 8 hours. Then can I keep up to 06 or 08 hours supine position postural restriction....

Please guide me...


Thanks & regards

N. L. D. Prasad


Edit: Category changed; see also this post #1. [Helmut]

Complete thread:

Activity
 Admin contact
21,786 posts in 4,557 threads, 1,548 registered users;
online 11 (1 registered, 10 guests [including 6 identified bots]).
Forum time: Monday 00:55 CET (Europe/Vienna)

The history of statistics is like a telephone directory:
the plot is boring, full of numbers and the cast is endless.    Stephen Senn

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5