Postural restriction [Design Issues]

posted by lakshmiprasad – India, 2018-03-17 10:20 (2669 d 14:49 ago) – Posting: # 18563
Views: 6,873

Hi,

Good afternoon to all,

Please any one help to me on below mentioned.

I would like to know about the postural restriction of subjects after dosing. I have doubt on supine postural restriction.

Ex:

Generally Whenever i was wrote the protocol, based on product prescribed information i will make it the postural restriction 02 hours or 04 hours (based on the molecule Tmax i.e., 2, 4) supine position in case molecule will be created the somnolence.

Now my doubt is if molecule Tmax is 6 or 8 hours. Then can I keep up to 06 or 08 hours supine position postural restriction....

Please guide me...


Thanks & regards

N. L. D. Prasad


Edit: Category changed; see also this post #1. [Helmut]

Complete thread:

UA Flag
Activity
 Admin contact
23,428 posts in 4,929 threads, 1,687 registered users;
89 visitors (0 registered, 89 guests [including 16 identified bots]).
Forum time: 02:09 CEST (Europe/Vienna)

Anyone who conducts an argument by appealing to authority
is not using his intelligence;
he is just using his memory.    Leonardo da Vinci

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5