Within subject variability [Power / Sample Size]

posted by MaggieSantos – Portugal, 2018-03-15 23:51 (1837 d 23:26 ago) – Posting: # 18558
Views: 3,664

Dear all,

I am exploring the hypothesis to use the within subject variability obtained on conventional 2 way crossover bioequivalence study and apply it in scale average bioequivalence as described for a replicated design used for HVD or NTI.
I know that within subject variability of reference would be necessary, but I have no replicated design. My doubt is if these values have any relation somehow like, for instance, the first one is larger than the second one or there is no relationship at all?

Kind Regards


Edit: Category changed; see also this post #1. [Helmut]

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