Bioequivalence and Bioavailability Forum

other than 90% CI in BE study? [🇷 for BE/BA]

posted by Helmut  – Vienna, Austria, 2018-03-15 17:18 (2666 d 09:31 ago) – Posting: # 18554
Views: 10,542

Hi roro2907,

❝ I am just curious as I am reviewing a BE study which has used a 94.12 confidence interval. Do you have any ideas as to why this is?

As Yung-jin assumed it smells of a Two-Stage Design of the Potvin flavour. It would need a major rewrite of bear because we not only need an option to specify an adjusted α (which is always <0.05) but – if the study proceeded to the second stage – “stage” in the model. BTW, you might face different CIs in the future (see this presentation).

—
Dif-tor heh smusma 🖖🏼 Довге життя Україна! 
Helmut Schütz


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Complete thread:

• Error in Number of Subjects roro2907 2018-03-14 10:43 [🇷 for BE/BA] 
  • Error in Number of Subjects yjlee168 2018-03-14 11:07
    • Error in Number of Subjects roro2907 2018-03-14 11:28
      • Error in Number of Subjects yjlee168 2018-03-14 11:54
        • Error in Number of Subjects roro2907 2018-03-14 12:54
          • Error in Number of Subjects yjlee168 2018-03-14 13:07
            • Error in Number of Subjects roro2907 2018-03-14 13:08
              • Error in Number of Subjects yjlee168 2018-03-14 13:32
                • Error in Number of Subjects roro2907 2018-03-14 13:41
                • Error in Number of Subjects roro2907 2018-03-14 16:03
                  • other than 90% CI in BE study? yjlee168 2018-03-14 19:14
                    • other than 90% CI in BE study? roro2907 2018-03-15 10:19
                      • Is it a two-stage BE study? yjlee168 2018-03-15 11:48
                        • Is it a two-stage BE study? roro2907 2018-03-15 17:51
                      • other than 90% CI in BE study?Helmut 2018-03-15 16:18
                        • other than 90% CI in BE study? roro2907 2018-03-15 17:53
                          • Homework Helmut 2018-03-16 10:57