TIE depends on CVwR (and n) [RSABE / ABEL]

posted by Helmut Homepage – Vienna, Austria, 2018-02-28 14:48 (1541 d 04:49 ago) – Posting: # 18485
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Dear Pjs,

» […] study is passing the SCABE criteria.

If you are referring to the FDA’s RSABE approach, there is not problem with inflation of the Type I Error if (the true) CVwR ≥30%. Only with CVwR <30% problems might be massive (see this presentation).

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