Put the sickle to the corn [General Statistics]
Hi Nastia,
No worries. I was curious myself.
Or the dose regimen (as Relaxation suspected)?

Linear plot with enlarged time scale:
![[image]](img/uploaded/image499.png)
Your wish is my command. Data cemetery:
❝ I didn't want to doubt into results of your study,
No worries. I was curious myself.
❝ just wanted to point out that the results of miscorrelation between Cmax and AUC should be more dependent on the features of the specific study than on the drug itself.
Or the dose regimen (as Relaxation suspected)?
❝ […] is sampling time is adequate but comparing to the less rapid drug the difference in 30 minutes in elimination phase could give sufficiently more error in calculating AUC (one day for jinn as thousand years for man)?

❝ The last question about it: what was the mean T1/2 (from these abrupt profiles I may suspect less than known in literature 20 minutes)?
Linear plot with enlarged time scale:
![[image]](img/uploaded/image499.png)
Your wish is my command. Data cemetery:
tlag tmax t½ Cmax AUCt AUCext
T 5 (0, 5) 40 (30, 57) 22 (6.5) 5.36 (24.3) 6.03 (15.6) 6.37 (5.81, 6.94)
R 5 (0, 5) 35 (30, 50) 23 (5.2) 5.03 (25.9) 5.48 (21.0) 5.45 (4.89, 6.73)
tlag, tmax
minutes; median (quartiles)t½
minutes; harmonic mean (jackknife SD)Cmax
µg/mL; geometric mean (CV%)AUCt
h×µg/mL; geometric mean (CV%)AUCext
100(AUCt–AUC∞)/AUC∞; median (quartiles)—
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Helmut Schütz
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Science Quotes
Dif-tor heh smusma 🖖🏼 Довге життя Україна!
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Helmut Schütz
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The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes
Complete thread:
- Power and type I adjustment for 222BE when several PK prams considered Louis52 2018-02-07 21:04 [General Statistics]
- Power and type I adjustment for 222BE when several PK prams considered ElMaestro 2018-02-07 22:37
- Power of two combined TOST d_labes 2018-02-08 14:12
- The mysterious ρ Helmut 2018-02-08 21:40
- ρ ρ ρ your boat ElMaestro 2018-02-09 09:58
- ρ ρ ρ your boat Helmut 2018-02-09 19:20
- ...and a bonus question ElMaestro 2018-02-09 11:32
- ...and a bonus question Helmut 2018-02-09 19:43
- If u see a BEar don't forget to R oaρ Astea 2018-02-09 20:47
- package install failed d_labes 2018-02-11 13:23
- If u see a BEar don't forget to R oaρ Astea 2018-02-09 20:47
- ...and a bonus question Helmut 2018-02-09 19:43
- The mysterious ρ -between or within studies d_labes 2018-02-11 15:57
- The mysterious ρ -between or within studies Helmut 2018-02-11 17:31
- The mysterious ρ -between or within studies d_labes 2018-02-11 19:21
- The mysterious ρ within studies Helmut 2018-02-11 22:44
- The mysterious ρ within studies nobody 2018-02-12 09:08
- The mysterious ρ within studies Helmut 2018-02-11 22:44
- The mysterious ρ -between or within studies d_labes 2018-02-11 19:21
- The mysterious ρ -between or within studies Astea 2018-02-11 17:34
- The mysterious ρ -between or within studies d_labes 2018-02-11 19:36
- The mysterious ρ within studies Helmut 2018-02-11 22:48
- The mysterious ρ -between or within studies Helmut 2018-02-11 17:31
- ρ ρ ρ your boat ElMaestro 2018-02-09 09:58
- The mysterious ρ Helmut 2018-02-08 21:40
- Power and type I adjustment for 222BE when several PK prams considered ElMaestro 2018-02-11 18:43
- Power and type I adjustment for 222BE when several PK prams considered nobody 2018-02-12 09:10
- reminds me of something ElMaestro 2018-02-12 09:18
- reminds me of something nobody 2018-02-12 09:38
- Hammer to fall Astea 2018-02-12 18:37
- Put the sickle to the corn Helmut 2018-02-13 01:37
- Put the sickle to the corn Astea 2018-02-13 08:27
- Put the sickle to the cornHelmut 2018-02-13 12:45
- Put the sickle to the corn Relaxation 2018-02-13 10:37
- multiple units, lag-times Helmut 2018-02-13 13:31
- Put the sickle to the corn Astea 2018-02-13 08:27
- Put the sickle to the corn Helmut 2018-02-13 01:37
- Hammer to fall Astea 2018-02-12 18:37
- reminds me of something nobody 2018-02-12 09:38
- reminds me of something ElMaestro 2018-02-12 09:18
- Power and type I adjustment for 222BE when several PK prams considered nobody 2018-02-12 09:10