Put the sickle to the corn [General Statistics]
Dear Helmut!
Very sorry about that! I didn't want to doubt into results of your study, just wanted to point out that the results of miscorrelation between Cmax and AUC should be more dependent on the features of the specific study than on the drug itself.
Is it possible to expect large AUCresid for ASA when sampling time is 12 hours?
That's perfect. But than may it be connected with fast elimination of ASA? That is sampling time is adequate but comparing to the less rapid drug the difference in 30 minutes in elimination phase could give sufficiently more error in calculating AUC (one day for jinn as thousand years for man)?
The last question about it: what was the mean T1/2 (from these abrupt profiles I may suspect less than known in literature 20 minutes)?
I would prefer Nastia (that was Nabokov who first pointed out the similar pronounciation)
❝ I recalculated the entire study (October 1997!) from raw-data (nasty!).
Very sorry about that! I didn't want to doubt into results of your study, just wanted to point out that the results of miscorrelation between Cmax and AUC should be more dependent on the features of the specific study than on the drug itself.
❝ Maximum residual AUC in any of the 24 subjects 7%.
Is it possible to expect large AUCresid for ASA when sampling time is 12 hours?
❝ Hhm. 00:05, 00:10...
That's perfect. But than may it be connected with fast elimination of ASA? That is sampling time is adequate but comparing to the less rapid drug the difference in 30 minutes in elimination phase could give sufficiently more error in calculating AUC (one day for jinn as thousand years for man)?
The last question about it: what was the mean T1/2 (from these abrupt profiles I may suspect less than known in literature 20 minutes)?
❝ may I call you Nasty as well?
I would prefer Nastia (that was Nabokov who first pointed out the similar pronounciation)
—
"Being in minority, even a minority of one, did not make you mad"
"Being in minority, even a minority of one, did not make you mad"
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- The mysterious ρ -between or within studies d_labes 2018-02-11 15:57
- The mysterious ρ -between or within studies Helmut 2018-02-11 17:31
- The mysterious ρ -between or within studies d_labes 2018-02-11 19:21
- The mysterious ρ within studies Helmut 2018-02-11 22:44
- The mysterious ρ within studies nobody 2018-02-12 09:08
- The mysterious ρ within studies Helmut 2018-02-11 22:44
- The mysterious ρ -between or within studies d_labes 2018-02-11 19:21
- The mysterious ρ -between or within studies Astea 2018-02-11 17:34
- The mysterious ρ -between or within studies d_labes 2018-02-11 19:36
- The mysterious ρ within studies Helmut 2018-02-11 22:48
- The mysterious ρ -between or within studies Helmut 2018-02-11 17:31
- ρ ρ ρ your boat ElMaestro 2018-02-09 09:58
- The mysterious ρ Helmut 2018-02-08 21:40
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- Power and type I adjustment for 222BE when several PK prams considered nobody 2018-02-12 09:10
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- reminds me of something nobody 2018-02-12 09:38
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- Put the sickle to the cornAstea 2018-02-13 08:27
- Put the sickle to the corn Helmut 2018-02-13 12:45
- Put the sickle to the corn Relaxation 2018-02-13 10:37
- multiple units, lag-times Helmut 2018-02-13 13:31
- Put the sickle to the cornAstea 2018-02-13 08:27
- Put the sickle to the corn Helmut 2018-02-13 01:37
- Hammer to fall Astea 2018-02-12 18:37
- reminds me of something nobody 2018-02-12 09:38
- reminds me of something ElMaestro 2018-02-12 09:18
- Power and type I adjustment for 222BE when several PK prams considered nobody 2018-02-12 09:10