The mysterious ρ [General Statistics]
Hi Louis,
Current state of affairs about the mysterious ρ:
PS: No, I’m not underpowering my studies for Cmax. Some were so old that they were powered for an acceptance range of 75–133% or even 70–143%.
Was too lazy to browse through the protocols…
❝ But no one knows, at least not me, to what number the correlation should be set in practice.
❝ The authors team of the R package PowerTOST
is currently discussing that theme. May be we came out with some aid in the near future.
Current state of affairs about the mysterious ρ:
Runtime 0.78 seconds. 6176 subjects in 124 data sets of 98 2×2×2 studies (74 analytes).
Evaluated by: lm(log(PK) ~ sequence+subject+period+treatment, data=study)
PE.AUC[study] <- exp(summary(model.AUC)$coef["treatmentT", "Estimate"])
PE.Cmax[study] <- exp(summary(model.Cmax)$coef["treatmentT", "Estimate"])
model.rho <- lm(PE.Cmax ~ PE.AUC)
rho <- sqrt(summary(model.rho)$r.squared)
rho : 0.6983
PS: No, I’m not underpowering my studies for Cmax. Some were so old that they were powered for an acceptance range of 75–133% or even 70–143%.

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Science Quotes
Dif-tor heh smusma 🖖🏼 Довге життя Україна!
![[image]](https://static.bebac.at/pics/Blue_and_yellow_ribbon_UA.png)
Helmut Schütz
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The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes
Complete thread:
- Power and type I adjustment for 222BE when several PK prams considered Louis52 2018-02-07 21:04 [General Statistics]
- Power and type I adjustment for 222BE when several PK prams considered ElMaestro 2018-02-07 22:37
- Power of two combined TOST d_labes 2018-02-08 14:12
- The mysterious ρHelmut 2018-02-08 21:40
- ρ ρ ρ your boat ElMaestro 2018-02-09 09:58
- ρ ρ ρ your boat Helmut 2018-02-09 19:20
- ...and a bonus question ElMaestro 2018-02-09 11:32
- ...and a bonus question Helmut 2018-02-09 19:43
- If u see a BEar don't forget to R oaρ Astea 2018-02-09 20:47
- package install failed d_labes 2018-02-11 13:23
- If u see a BEar don't forget to R oaρ Astea 2018-02-09 20:47
- ...and a bonus question Helmut 2018-02-09 19:43
- The mysterious ρ -between or within studies d_labes 2018-02-11 15:57
- The mysterious ρ -between or within studies Helmut 2018-02-11 17:31
- The mysterious ρ -between or within studies d_labes 2018-02-11 19:21
- The mysterious ρ within studies Helmut 2018-02-11 22:44
- The mysterious ρ within studies nobody 2018-02-12 09:08
- The mysterious ρ within studies Helmut 2018-02-11 22:44
- The mysterious ρ -between or within studies d_labes 2018-02-11 19:21
- The mysterious ρ -between or within studies Astea 2018-02-11 17:34
- The mysterious ρ -between or within studies d_labes 2018-02-11 19:36
- The mysterious ρ within studies Helmut 2018-02-11 22:48
- The mysterious ρ -between or within studies Helmut 2018-02-11 17:31
- ρ ρ ρ your boat ElMaestro 2018-02-09 09:58
- The mysterious ρHelmut 2018-02-08 21:40
- Power and type I adjustment for 222BE when several PK prams considered ElMaestro 2018-02-11 18:43
- Power and type I adjustment for 222BE when several PK prams considered nobody 2018-02-12 09:10
- reminds me of something ElMaestro 2018-02-12 09:18
- reminds me of something nobody 2018-02-12 09:38
- Hammer to fall Astea 2018-02-12 18:37
- Put the sickle to the corn Helmut 2018-02-13 01:37
- Put the sickle to the corn Astea 2018-02-13 08:27
- Put the sickle to the corn Helmut 2018-02-13 12:45
- Put the sickle to the corn Relaxation 2018-02-13 10:37
- multiple units, lag-times Helmut 2018-02-13 13:31
- Put the sickle to the corn Astea 2018-02-13 08:27
- Put the sickle to the corn Helmut 2018-02-13 01:37
- Hammer to fall Astea 2018-02-12 18:37
- reminds me of something nobody 2018-02-12 09:38
- reminds me of something ElMaestro 2018-02-12 09:18
- Power and type I adjustment for 222BE when several PK prams considered nobody 2018-02-12 09:10