AUC=f·D/CL [Study As­sess­ment]

posted by ssussu – China, 2018-02-08 11:21  – Posting: # 18380
Views: 6,061

Hi Helmut,

As I simulate 3 condition of infusion by WinNonlin PK Modeling,
1. infusion by constant rate for 30min and complete the infusion at 30min;
2. infusion 15min and stop for 5min and speed up the infusion rate to complete at 30min;
3. infusion 15min and stop for 5min and keep the same infusion rate and complete at 35min.
below is what i get:
[image]

It's different from what you have present. Now I am confused, I don't know why.:confused:
Hope to discuss with you more.

Complete thread:

Activity
 Mix view
Bioequivalence and Bioavailability Forum |  Admin contact
19,871 posts in 4,212 threads, 1,364 registered users;
online 8 (0 registered, 8 guests [including 5 identified bots]).
Forum time (Europe/Vienna): 13:20 CEST

Multivariate analysis: A means of finding the answer
when you don’t know the question.    Stephen Senn

The BIOEQUIVALENCE / BIOAVAILABILITY FORUM is hosted by
BEBAC Ing. Helmut Schütz
HTML5