AUC=f·D/CL [Study As­sess­ment]

posted by ssussu – China, 2018-02-08 11:21  – Posting: # 18380
Views: 7,185

Hi Helmut,

As I simulate 3 condition of infusion by WinNonlin PK Modeling,
1. infusion by constant rate for 30min and complete the infusion at 30min;
2. infusion 15min and stop for 5min and speed up the infusion rate to complete at 30min;
3. infusion 15min and stop for 5min and keep the same infusion rate and complete at 35min.
below is what i get:

It's different from what you have present. Now I am confused, I don't know why.:confused:
Hope to discuss with you more.

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