Bioequivalence and Bioavailability Forum • To pool or not to pool

To pool or not to pool [🇷 for BE/BA]

posted by d_labes – Berlin, Germany, 2018-01-28 14:52 (2274 d 00:34 ago) – Posting: # 18301
Views: 13,295

Dear Öberster Größter Meister!

❝ Please give me a good reason to believe all those factors (plus all the ones I forgot) are the same across just any two studies. You pick and show me. Until then I consider pooled CV's a curiosity as useful as headmounted toilet paper etc.

Please hav a look at Guersey McPearson's prose, Essay "A dip in the Pool":

Quote: "It seems to me that people who object to pooling different studies but would quite happily accept any one of them on its own, if only it were large enough, for the purpose of informing medical decision making, should be given thinking lessons."

More in the whole essay.

—
Regards,

Detlew

Complete thread:

Function CVpooled (package PowerTOST) Elena777 2018-01-21 08:53 [🇷 for BE/BA]
- Function CVpooled (lengthy answer) Helmut 2018-01-21 17:21
  - Function CVpooled (lengthy answer) Elena777 2018-01-27 10:11
- Function CVpooled (package PowerTOST) ElMaestro 2018-01-27 22:28
  - Common sense Helmut 2018-01-28 00:27
    - Common sense ElMaestro 2018-01-28 08:43
      - Alzheimer’s Helmut 2018-01-28 11:38
  - To pool or not to poold_labes 2018-01-28 13:52
- Function CVpooled (package PowerTOST) ElMaestro 2018-01-29 00:07
  - Pooling is fooling? Helmut 2018-01-29 17:53
    - Pooling is fooling? nobody 2018-01-29 19:21
      - Life is good ElMaestro 2018-01-30 18:23
        
        Life is good nobody 2018-01-30 18:31
        
        OT: Flags Helmut 2018-01-31 01:47
        
        OT: Flags nobody 2018-01-31 10:17
        
        OT: Flags ElMaestro 2018-01-31 11:02
        OT: Flags Helmut 2018-01-31 11:16
        
        OT: Flags nobody 2018-01-31 11:22
        
        OT: Flags Helmut 2018-01-31 11:38
        
        OT: Flags nobody 2018-01-31 12:28
        
        OT: Flags Helmut 2018-01-31 17:18
        
        OT: Flags nobody 2018-01-31 17:32
        
        OT: Flags Helmut 2018-01-31 19:00