Line extension [Design Issues]

posted by Helmut Homepage – Vienna, Austria, 2018-01-23 18:40 (2276 d 13:54 ago) – Posting: # 18278
Views: 4,298

Hi Mikkabel,

Luckily you are not exceeding the recommended dose of the originator. Hence, I would opt for a simple line extension (T2 vs. 2×T1) since you can expect a better match than in BE – which is possible as well (T2 vs. 2×R).
I don’t see how you could perform a dose-proportionality study with just two levels (zero degrees of freedom).

Dif-tor heh smusma 🖖🏼 Довге життя Україна! [image]
Helmut Schütz
[image]

The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes

Complete thread:

UA Flag
Activity
 Admin contact
22,986 posts in 4,823 threads, 1,661 registered users;
72 visitors (0 registered, 72 guests [including 5 identified bots]).
Forum time: 09:34 CEST (Europe/Vienna)

Art is “I”; science is “we”.    Claude Bernard

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5