Bioequivalence and Bioavailability Forum • effect of tabacco on diclofenac metabolism

effect of tabacco on diclofenac metabolism [Design Issues]

posted by Norah – Tunisia, 2018-01-23 09:11 (1889 d 08:28 ago) – Posting: # 18256
Views: 3,596
(edited by Ohlbe on 2018-01-23 11:12)

thank u relaxation :)

diclofenac is a substrate of cytochrome P450 2C9 / tobacco is an inducer of cytochromes P450 1A1, 1A2 and 2E1
therefore no effect of tobacco on the metabolism of diclofenac.

Edit: two posts merged. You can edit your messages during 24h, which is preferred over answering your own message [Ohlbe]

Complete thread:

effect of tabacco on diclofenac metabolism Norah 2018-01-22 14:50 [Design Issues]
- effect of tabacco on diclofenac metabolism Relaxation 2018-01-22 18:26
  - Substrate for CYP1A1? Helmut 2018-01-22 18:43
    - Substrate for CYP1A1? Norah 2018-01-23 08:11
  - effect of tabacco on diclofenac metabolismNorah 2018-01-23 08:11