Substrate for CYP1A1? [Design Issues]
Hi Relaxation,
I agree. In general I would not worry too much about including mild to moderate smokers unless a drug is mainly (!) metabolized by CYP1A1.
@Norah: Check the literature whether diclofenac is a substrate for CYP1A1 (I don’t think so).
I agree. In general I would not worry too much about including mild to moderate smokers unless a drug is mainly (!) metabolized by CYP1A1.
@Norah: Check the literature whether diclofenac is a substrate for CYP1A1 (I don’t think so).
—
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Dif-tor heh smusma 🖖🏼 Довге життя Україна!
![[image]](https://static.bebac.at/pics/Blue_and_yellow_ribbon_UA.png)
Helmut Schütz
![[image]](https://static.bebac.at/img/CC by.png)
The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes
Complete thread:
- effect of tabacco on diclofenac metabolism Norah 2018-01-22 14:50 [Design Issues]
- effect of tabacco on diclofenac metabolism Relaxation 2018-01-22 18:26
- Substrate for CYP1A1?Helmut 2018-01-22 18:43
- Substrate for CYP1A1? Norah 2018-01-23 08:11
- effect of tabacco on diclofenac metabolism Norah 2018-01-23 08:11
- Substrate for CYP1A1?Helmut 2018-01-22 18:43
- effect of tabacco on diclofenac metabolism Relaxation 2018-01-22 18:26