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RegisterSubstrate for CYP1A1? [Design Issues]
posted by Helmut 
– Vienna, Austria, 2018-01-22 19:43 (2725 d 13:05 ago) – Posting: # 18252
Views: 4,729
Hi Relaxation,
I agree. In general I would not worry too much about including mild to moderate smokers unless a drug is mainly (!) metabolized by CYP1A1.
@Norah: Check the literature whether diclofenac is a substrate for CYP1A1 (I don’t think so).
I agree. In general I would not worry too much about including mild to moderate smokers unless a drug is mainly (!) metabolized by CYP1A1.
@Norah: Check the literature whether diclofenac is a substrate for CYP1A1 (I don’t think so).
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Dif-tor heh smusma 🖖🏼 Довге життя Україна!
Helmut Schütz
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Complete thread:
- effect of tabacco on diclofenac metabolism Norah 2018-01-22 14:50 [Design Issues]
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- effect of tabacco on diclofenac metabolism Relaxation 2018-01-22 18:26
- Substrate for CYP1A1?Helmut 2018-01-22 18:43
- Substrate for CYP1A1? Norah 2018-01-23 08:11
- effect of tabacco on diclofenac metabolism Norah 2018-01-23 08:11
- Substrate for CYP1A1?Helmut 2018-01-22 18:43
- effect of tabacco on diclofenac metabolism Relaxation 2018-01-22 18:26
Ing. Helmut Schütz