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RegisterCV values in BE studies: intra, or inter, or total? [Study Assessment]
Hi
I checked the table... That's not the intrasubject CV. That's just the CV from (SD/Mean)*100.
Same answer from your 2nd question (I didn't look but I assume you were referring to a result that has similar output format as in Mean(CV)).
In the world of BE we deal with CVintra because that's what we are interested in since that's one of the driving force in computing the 90% CI goal post for BE. We do care about inter and CVtotal as well depending on the type of BE study design we are going after (crossover or parallel).
J
❝ Ln Cmax(ng/ml) […]: Mean (CV) = 1212.09 (28.7)
I checked the table... That's not the intrasubject CV. That's just the CV from (SD/Mean)*100.
Same answer from your 2nd question (I didn't look but I assume you were referring to a result that has similar output format as in Mean(CV)).
❝ Which kind of CV is performed in my examples? And in general which kind of CV is usually performed in reports of BE studies? Is it CVintra, or CVinter, or CVtotal?
In the world of BE we deal with CVintra because that's what we are interested in since that's one of the driving force in computing the 90% CI goal post for BE. We do care about inter and CVtotal as well depending on the type of BE study design we are going after (crossover or parallel).
J
Complete thread:
- CV values in BE studies: intra, or inter, or total? Elena777 2018-01-20 12:31 [Study Assessment]
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- CV values in BE studies: intra, or inter, or total?jag009 2018-01-20 19:18
- CV values in BE studies: intra, or inter, or total? Elena777 2018-01-20 21:10
- CV values in BE studies: intra, or inter, or total? jag009 2018-01-21 03:17
- CV values in BE studies: intra, or inter, or total? Elena777 2018-01-21 08:21
- CV values in BE studies: intra, or inter, or total? jag009 2018-01-21 03:17
- CV values in BE studies: intra, or inter, or total? Elena777 2018-01-20 21:10
- CV values in BE studies: intra, or inter, or total? Helmut 2018-01-21 17:33
- CV values in BE studies: intra, or inter, or total? ElMaestro 2018-01-21 18:17
- CV values in BE studies: intra, or inter, or total? Elena777 2018-01-27 09:57
- CV values in BE studies: intra, or inter, or total? Louis52 2018-02-07 20:22
- CV values in BE studies: intra, or inter, or total? Helmut 2018-02-07 20:31
- CV values in BE studies: intra, or inter, or total? Rosy 2019-02-19 18:33
- PowerTOST: CVfromCI Helmut 2019-02-20 13:00
- PowerTOST: CVfromCI -> CI.BE d_labes 2019-02-20 14:12
- PowerTOST: CVfromCI Rosy 2019-02-20 15:25
- type known.designs() in PowerTOST Helmut 2019-02-20 16:14
- type known.designs() in PowerTOST Rosy 2019-02-20 17:14
- type known.designs() in PowerTOST Helmut 2019-02-20 16:14
- PowerTOST: CVfromCI Helmut 2019-02-20 13:00
- CV values in BE studies: intra, or inter, or total? Rosy 2019-02-19 18:33
- CV values in BE studies: intra, or inter, or total? Helmut 2018-02-07 20:31
- CV values in BE studies: intra, or inter, or total? Louis52 2018-02-07 20:22
- CV values in BE studies: intra, or inter, or total? Elena777 2018-01-27 09:57
- CV values in BE studies: intra, or inter, or total?jag009 2018-01-20 19:18
Ing. Helmut Schütz