EEU - pharmacokinetic equation??? [Power / Sample Size]

posted by mittyri  – Russia, 2017-12-29 15:11 (2702 d 04:21 ago) – Posting: # 18126
Views: 35,430

Hi Yura,

❝ So I understand: imagine the power analysis and draw a conclusion (at low power) that since bioequivalence is established, a posteriori power rating does not affect the findings of the study

Yep. Once again: to be lucky is not a crime :-D
and vice versa: if the post-hoc power is -> 100%, you're a hero even if the study was overpowered de facto (i.e. CI [0.98-1.03]).

❝ More interesting question: the pharmacokinetic equation and its analysis ... :confused:

Good question! Next question!
Seems like they are interested in PK model which is not permitted. No clue so far :-|

Kind regards,
Mittyri

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Pharmacokinetics may be simply defined as
what the body does to the drug,
as opposed to pharmacodynamics, which may be defined as
what the drug does to the body.    Leslie Z. Benet

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