“Forced BE” 101 [Power / Sample Size]

posted by kms.srinivas – India, 2017-12-27 13:41 (2273 d 13:20 ago) – Posting: # 18098
Views: 33,096

Dear Helmut,
Much pleasure with your reply.

❝ study planned for 90% power: The chance to obtain a post hoc power of ≥95% is ~35%.


Is it a thumb rule? how it should be calculated?

❝ It only means that

❝    – the CV was lower and/or

❝    – the GMR closer to 1 and/or

❝    – you had less dropouts than assumed.


Yes, on getting posthoc analysis, i found three aspects what you said:
After experiment, it came to know that
1. CV getting lower
2. GMR close to 1
3. No dropouts/withdrawls (though prior consideration of 10% dropouts)

Complete thread:

UA Flag
Activity
 Admin contact
22,940 posts in 4,812 threads, 1,639 registered users;
36 visitors (0 registered, 36 guests [including 7 identified bots]).
Forum time: 03:02 CET (Europe/Vienna)

Those people who think they know everything
are a great annoyance to those of us who do.    Isaac Asimov

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5