Bioequivalence and Bioavailability Forum • Reference-scaling: USE PowerTOST

Reference-scaling: USE PowerTOST [Power / Sample Size]

posted by Astea – Russia, 2017-12-01 15:16 (2328 d 04:19 ago) – Posting: # 18031
Views: 14,431

Dear Helmut!

Thank you for enlightening this question!

The advantage of R is doubtless. I just wanted to show FARTSSIE not worser than other rude methods of sample size estimation (remember nomogram and so on).

(Sorry, I've made a mistake in the previous post, the data from the paper refers to partial replicate design 2x3x3.)

By the way, for extreme numbers from the paper by Endrényi L, Tóthfalusi L. we also get slightly underpowered study:

power.scABEL(CV=0.8,n=54,theta0=0.95,design="2x3x3")

[1] 0.79917

power.scABEL(CV=0.8,n=72,theta0=0.9,design="2x3x3")

[1] 0.79782

—
"Being in minority, even a minority of one, did not make you mad"

Complete thread:

Sample Size Estimation -Replicate design- BE limits cakhatri 2017-11-30 09:44
- Reference-scaling: Don’t use FARTSSIE! Helmut 2017-11-30 10:58
  - Reference-scaling: Don’t use FARTSSIE? Astea 2017-11-30 22:50
    - Reference-scaling: Don’t use FARTSSIE! Helmut 2017-12-01 11:42
      - Reference-scaling: USE PowerTOSTAstea 2017-12-01 14:16
        
        Reference-scaling: USE PowerTOST cakhatri 2017-12-04 06:00
        
        Reference-scaling: USE PowerTOST Helmut 2017-12-04 15:07
        
        Reference-scaling: USE PowerTOST cakhatri 2017-12-05 05:33
        
        Use PowerTOST d_labes 2017-12-06 09:52
        
        Use PowerTOST, not Endrényi L, Tóthfalusi L tables mittyri 2017-12-07 16:03
        
        Precision in Endrényi L, Tóthfalusi L tables d_labes 2017-12-07 18:21
        
        Precision of PowerTOST mittyri 2017-12-08 22:56
        
        Precision of PowerTOST Helmut 2017-12-09 17:00
        
        Precision of PowerTOST mittyri 2017-12-09 21:05
        
        Precision of PowerTOST Astea 2017-12-10 00:10
        
        Precision of PowerTOST Helmut 2017-12-10 20:27
        
        Precision of PowerTOST Astea 2017-12-10 21:13
  - Reference-scaling: Don’t use FARTSSIE! pjs 2018-02-09 13:08
    - Reference-scaling: Don’t use FARTSSIE! Helmut 2018-02-09 20:15