Bioequivalence and Bioavailability Forum • PK parameters from multiple doses

PK parameters from multiple doses [PK / PD]

posted by SDavis – UK, 2017-11-24 23:09 (2704 d 13:16 ago) – Posting: # 18003
Views: 10,288

If I assume linear PK etc, with a model I can estimate all PK parameters e.g. Cmax, etc on Day 1. It is also possible you might not be at steady state on Day 15, if you have a long half-life.

Simon.

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Simon
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Complete thread:

Single PK parameters from multiple PK parameters asjrm 2017-11-19 00:44 [PK / PD]
- Single PK parameters from multiple PK parameters jag009 2017-11-19 06:32
- PK parameters from multiple doses Helmut 2017-11-19 10:24
  - PK parameters from multiple doses Yura 2017-11-21 11:48
  - PK parameters from multiple doses SDavis 2017-11-24 10:59
    - PK parameters from multiple doses nobody 2017-11-24 16:07
      - PK parameters from multiple dosesSDavis 2017-11-24 22:09
        
        PK parameters from multiple doses nobody 2017-11-27 14:13
        
        PK parameters from multiple doses SDavis 2017-11-28 11:34
        
        PK parameters from multiple doses nobody 2017-11-28 11:51
        
        PK parameters from multiple doses SDavis 2017-11-28 11:54
- Single PK parameters from multiple PK parameters nobody 2017-11-21 14:54