Bioequivalence and Bioavailability Forum • PK parameters from multiple doses

PK parameters from multiple doses [PK / PD]

posted by Yura – Belarus, 2017-11-21 12:48 (2780 d 03:48 ago) – Posting: # 17997
Views: 10,607

Hi Helmut
AUC is truncated with an interval of reception (in the morning and in the evening - 12 hours).
what 24 hours? if after the first dose - it is also 12 hours. Perhaps, the AUCt / AUCi criterion will be less than 80%.
Thank you

Complete thread:

Single PK parameters from multiple PK parameters asjrm 2017-11-19 00:44 [PK / PD]
- Single PK parameters from multiple PK parameters jag009 2017-11-19 06:32
- PK parameters from multiple doses Helmut 2017-11-19 10:24
  - PK parameters from multiple dosesYura 2017-11-21 11:48
  - PK parameters from multiple doses SDavis 2017-11-24 10:59
    - PK parameters from multiple doses nobody 2017-11-24 16:07
      - PK parameters from multiple doses SDavis 2017-11-24 22:09
        
        PK parameters from multiple doses nobody 2017-11-27 14:13
        
        PK parameters from multiple doses SDavis 2017-11-28 11:34
        
        PK parameters from multiple doses nobody 2017-11-28 11:51
        
        PK parameters from multiple doses SDavis 2017-11-28 11:54
- Single PK parameters from multiple PK parameters nobody 2017-11-21 14:54