## calculation of 90% CI for continuous variable in clinical endpoint studies [General Statistics]

Hello El-Maestro,

Thankyou for the reply.

How can we will calculate 90% CI for ratio of means of untransformed continuous variable using PROC GLM in SAS.

Please help me in this regards.

Thankyou

GM.

Thankyou for the reply.

❝

❝ the tradition is to use 80.00%-125.00% for a ratio of continuous variables. This makes extremely good sense under a certain set of assumptions.

❝

❝ You refer to section 21 of the guidance, but this does not relate to continuous variables. It applies to dichotomous variables instead.

❝

❝ Rule of thumb: For a difference, the acceptance range is symmetric. For a ratio the lower acceptance limit equals the reciprocal upper limit, naturally. Most BE issues you will come across have elements of both if logs are involved.

How can we will calculate 90% CI for ratio of means of untransformed continuous variable using PROC GLM in SAS.

Please help me in this regards.

Thankyou

GM.

—

Best Regards,

GM

Best Regards,

GM

### Complete thread:

- calculation of 90% CI for continuous variable in clinical endpoint studies GM 2017-11-17 04:55 [General Statistics]
- calculation of 90% CI for continuous variable in clinical endpoint studies ElMaestro 2017-11-18 21:17
- calculation of 90% CI for continuous variable in clinical endpoint studiesGM 2017-11-19 12:13
- calculation of 90% CI for continuous variable in clinical endpoint studies ElMaestro 2017-11-20 20:41
- calculation of 90% CI for continuous variable in clinical endpoint studies GM 2017-11-21 06:02
- calculation of 90% CI for continuous variable in clinical endpoint studies DavidManteigas 2017-11-21 10:01

- calculation of 90% CI for continuous variable in clinical endpoint studies GM 2017-11-21 06:02

- calculation of 90% CI for continuous variable in clinical endpoint studies ElMaestro 2017-11-20 20:41

- calculation of 90% CI for continuous variable in clinical endpoint studiesGM 2017-11-19 12:13

- calculation of 90% CI for continuous variable in clinical endpoint studies ElMaestro 2017-11-18 21:17