calculation of 90% CI for continuous variable in clinical endpoint studies [General Sta­tis­tics]

posted by GM – India, 2017-11-17 05:55 (2029 d 03:01 ago) – Posting: # 17986
Views: 5,290

Hello All,

As I am new to the endpoint studies, how can we calculate 90% CI for continuous variable in clinical endpoint studies?

As per my understanding, there are two ways. One is ±20 rule for the difference of means and 80-120% rule for ratio of means of un-transformed data. Based on this reference 90% CI Calculation

But as per OGD, the 90%CI should lies in 80-125% for un-transformed data. Please see the point no.21 in the OGD (see Clindamycin Phosphate).

This is :confused: me a lot. Please clarify.

Edit: URL corrected. Please don’t link to a Google-India search term. [Helmut]

Best Regards,

Complete thread:

UA Flag
 Admin contact
22,620 posts in 4,741 threads, 1,612 registered users;
24 visitors (0 registered, 24 guests [including 12 identified bots]).
Forum time: 09:56 CEST (Europe/Vienna)

Outside his own ever-narrowing field of specialization,
a scientist is a layman.
What members of an academy of science have in common
is a certain form of semiparasitic living.    Erwin Chargaff

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz