calculation of 90% CI for continuous variable in clinical endpoint studies [General Sta­tis­tics]

posted by GM – India, 2017-11-17 05:55 (2400 d 05:06 ago) – Posting: # 17986
Views: 5,897

Hello All,

As I am new to the endpoint studies, how can we calculate 90% CI for continuous variable in clinical endpoint studies?

As per my understanding, there are two ways. One is ±20 rule for the difference of means and 80-120% rule for ratio of means of un-transformed data. Based on this reference 90% CI Calculation

But as per OGD, the 90%CI should lies in 80-125% for un-transformed data. Please see the point no.21 in the OGD (see Clindamycin Phosphate).

This is :confused: me a lot. Please clarify.


Edit: URL corrected. Please don’t link to a Google-India search term. [Helmut]

Best Regards,
GM

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