Vd/F calculation in bear [🇷 for BE/BA]

posted by CECIF – Colombia, 2017-11-04 00:54 (2364 d 10:02 ago) – Posting: # 17968
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❝ uhh... since version 6.2? bear? the current version is 2.8.3 (as shown in my signature panel).


You are right, I meant 2.6.2. Sorry for the brain fart. :-(


❝ What was your selection for trapezoidal method? linear-up/log-down (default method) or all linear? That could make a little differences.


My selection was default


❝ [...] What about Cl/F?



Now That I looked for teh code as Helmut told me is all very clear. It seems however that both Vd/F and Cl/F are affected by the same misscalculation from AUC0inf. I will check with the other methods and tell you later.

Anyway, your answers were very helpful. Many thanks

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