Bioequivalence and Bioavailability Forum • Atorvastatin intra-subject Variability

Atorvastatin intra-subject Variability [Study Assessment]

posted by nobody – 2017-09-27 10:11 – Posting: # 17832
Views: 3,837

» Chance?
Maybe, but...

» Better assay?
No

» Design differences?
How?

» Lesser within-batch variability (-ies) than in the studies you compare to?
Variability has been attributed to various physiological sources, including e.g. liver function, transporter status:

https://www.ncbi.nlm.nih.gov/pubmed/22167570
https://www.ncbi.nlm.nih.gov/pubmed/21548957
https://www.ncbi.nlm.nih.gov/pubmed/20818835

—
Kindest regards, nobody

Complete thread:

Atorvastatin intra-subject Variability Amira 2017-09-26 12:26
- Atorvastatin intra-subject Variability ElMaestro 2017-09-26 12:51
  - Atorvastatin intra-subject Variabilitynobody 2017-09-27 10:11
    - Atorvastatin intra-subject Variability Helmut 2017-09-27 11:05

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