CVs for untransformed data [Software]

posted by Helmut Homepage – Vienna, Austria, 2017-09-02 17:57 (2717 d 09:02 ago) – Posting: # 17765
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Hi mittyri,

❝ citing the WNL guide:

intrasubject CV = sqrt(Var(Residual)) / RefLSM

where RefLSM is the Least Squares Mean of the reference treatment.


❝ For me even the formula above is strange. You are dividing overall standard deviation (calculated for both T and R) by LSMean of reference product only. Does that mean that if we inverse R to T, CV should change too?


Not necessarily should but will. I suggest dividing by the (weighted) global mean.

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