Phoenix Template v1.5 for the EMA’s ABEL [Software]

posted by Helmut Homepage – Vienna, Austria, 2017-08-23 21:45 (2377 d 21:05 ago) – Posting: # 17746
Views: 5,910

Dear all,

Michael (aka “mittyri” here and “mittyright” at Certara’s forum) and I updated the Phoenix WinNonlin template for the EMA’s ABEL ([image] free download).
The template was developed in PHX and tested in PHX The template was cross-validated with 26 data sets (all designs, up to 360 subjects) against SAS v9.4 (Methods A, B, C), R v3.4.1 (A, B), STATISTICA (A, B), and partly (Q&A data sets I and II; Methods A, B) against STaTa v14, SPSS v22, and JMP v10.2 As usual, use at your own risk.

In your project delete all PDFs in the Documents folder in order to reduce its size. The run-time is slightly better than in previous versions but needs patience. Since Phoenix swaps inter­mediate results to the system drive, it will take a while to complete. On my machine (with fast solid-state drives) execution of the Q&A’s data set I takes 2:15 minutes (Phoenix 6.4) and 1:50 minutes (Phoenix 7.0). If you have a hard drive, it may take substantially (?) longer.

Reports of defects and especially experiences with Windows installed on a hard drive are welcome at the
Certara Forum (registration necessary).

  1. Balaam LN. A Two-Period Design with t2 Experimental Units. Biometrics 1968; 24(1): 61–73. doi:10.2307/2528460.
  2. Schütz H, Labes D, Tomashevskiy M, González de la Parra M, Shitova A, Fuglsang A. Reference Datasets for Studies in a Replicate Design Intended for Average Bioequivalence with Expanding Limits. AAPS J. 2020; 22: 44. doi:10.1208/s12248-020-0427-6.

Dif-tor heh smusma 🖖🏼 Довге життя Україна! [image]
Helmut Schütz

The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes

Complete thread:

UA Flag
 Admin contact
22,912 posts in 4,806 threads, 1,635 registered users;
36 visitors (0 registered, 36 guests [including 11 identified bots]).
Forum time: 17:51 CET (Europe/Vienna)

[…] an inappropriate study design is incapable of answering
a research question, no matter how careful the subsequent
methodology, conduct, analysis, and interpretation:
Flawless execution of a flawed design achieves nothing worthwhile.    J. Rick Turner

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz