Bioequivalence and Bioavailability Forum • sample size in bioequivalence studies

sample size in bioequivalence studies [Power / Sample Size]

posted by daryazyatina – Ukraine, 2017-08-03 12:08 (2448 d 08:38 ago) – Posting: # 17648
Views: 18,729

Hi, BE-proff. Thank you for your answer.

❝ Results must be different because PowerTOST uses iterative method for calculation.

Have you looked at the formula what I used? There is also used an iterative method.

❝ AFAIK, PowerTOST is used worldwide and no claims from regulators have been received.

It's good. But I asked another question.
I used formula from book:

❝ ❝ Shein-Chung Chow, Jun Shao and Hansheng Wang "Sample size calculations in clinical research" Copyright © 2003 by Marcel Dekker (Chapter 10. Bioequivalence Testing)

and also any claims from regulators have not been received.

Complete thread:

sample size in bioequivalence studies daryazyatina 2017-08-03 09:34
- sample size in bioequivalence studies BE-proff 2017-08-03 09:55
  - sample size in bioequivalence studiesdaryazyatina 2017-08-03 10:08
- sample size in bioequivalence studies ElMaestro 2017-08-03 10:17
  - sample size in bioequivalence studies daryazyatina 2017-08-03 10:58
    - sample size in bioequivalence studies DavidManteigas 2017-08-03 12:40
      - sample size in bioequivalence studies daryazyatina 2017-08-03 13:46
      - Don’t use the formula by Chow, Shao, Wang! Helmut 2017-08-03 15:37
        
        Don’t use the formula by Chow, Shao, Wang! daryazyatina 2017-08-03 15:52
        Don’t use the formula by Chow, Shao, Wang! DavidManteigas 2017-08-03 16:12
        
        Don’t use the formula by Chow, Shao, Wang! Helmut 2017-08-03 16:33
        
        Don’t use the Book by Chow, Shao, Wang! d_labes 2017-08-16 16:01
    - compromised power Helmut 2017-08-03 16:04
      - compromised power daryazyatina 2017-08-04 08:15
        
        terminology Helmut 2017-08-04 12:41
        
        terminology daryazyatina 2017-08-16 10:12
        
        terminology Helmut 2017-08-16 18:54
- sample size in bioequivalence studies balinskyi 2018-06-03 12:58

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