package ncappc in R [🇷 for BE/BA]
Good day, guys!
I have some data about concentration and time of this concentration from the literature data. I want to compare the data from WinNonLin with data from RStudio.
This .csv file I imported in RStudio.
and this code I used to calculate the pharmacokinetic parameters:
I need calculate elimination constant with time points from 5h to 24h.
After all RStudio calculate pharmacokinetic parameters BUT the elimination constant is incorrectly calculated.
What I do wrong?
Edit: Category changed; see also this post #1. [Helmut]
I have some data about concentration and time of this concentration from the literature data. I want to compare the data from WinNonLin with data from RStudio.
This .csv file I imported in RStudio.
ID,TIME,DV
1,0,0
1,0.33,358
1,0.66,585
1,1,645
1,1.33,792
1,1.66,761
1,2,882
1,2.5,926
1,3,1114
1,3.5,1111
1,4,1070
1,5,752
1,6,557
1,8,351
1,10,222
1,12,137
1,16,83
1,24,52
and this code I used to calculate the pharmacokinetic parameters:
ncappc(obsFile=system.file("extdata","concentrationb2.csv", package = "ncappc"),
concUnit = "ng/mL",
timeUnit = "h",
doseUnit = "g",
adminType = "extravascular",
doseType = "ns",
method = "linear",
printOut = FALSE,
psnOut=FALSE,
noPlot=TRUE,
LambdaExclude = c(0,0.33,0.66,1,1.33,1.66,2,2.5,3,3.5,4)
)
I need calculate elimination constant with time points from 5h to 24h.
After all RStudio calculate pharmacokinetic parameters BUT the elimination constant is incorrectly calculated.
What I do wrong?
Edit: Category changed; see also this post #1. [Helmut]
Complete thread:
- package ncappc in Rdaryazyatina 2017-07-25 15:12 [🇷 for BE/BA]
- package ncappc in R Helmut 2017-07-25 17:48
- package ncappc in R daryazyatina 2017-07-26 08:09
- package ncappc in R Helmut 2017-07-25 17:48