Bioequivalence and Bioavailability Forum

❝ Would be fun to simulate that. Makes a nice paper.

...same thought here, thought about reviving my old "S-plus" files with "retro-NONMEM" sim approach to study influence of analytical variability on parameters estimates in BE-trials But no time for the next months.

Have a special compound here, as some percentage of volunteers simply end up with low exposure, apparently nobody (no, not me...) knows why. Would be the classical situation were more samples is only more $$$, no better data, or?