lin-up/log-down any regulatory recommendation? [🇷 for BE/BA]

posted by pjs – India, 2017-05-21 21:08 (2819 d 10:31 ago) – Posting: # 17381
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Dear Helmut,

Thanks for the explanation :-). Is there any regulatory requirement for the use of linup-logdown method.

As u explained there could be more bias in the AUC estimation in case of missing samples.

Do this needs to be defined in the Protocol?

This could become crucial incase of borderline study results for AUC.

Regards
pjs

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