Bioequivalence and Bioavailability Forum • Difficulties with run NCA in BEAR

Difficulties with run NCA in BEAR [🇷 for BE/BA]

posted by Artem Gusev – Russia, Moscow, 2017-05-02 11:56 (3344 d 07:40 ago) – Posting: # 17289
Views: 10,515

Dear, yjlee168!

You are totaly right. The RDS was:

> readRDS("bearGUI.setup.rds")

                  Methods                Setting

1               run demo?                      0

2            study design                      0

3   single-/multiple-dose                      0

4       lambda_z estimate                      0

5         trapezoidal AUC                      1

6       BE criterion (LL)                     80

7                     ODA                      0

8            dose (in mg)                   <NA>

9         dosing interval                     24

10                  Tlast                    120

11                   pAUC                      0

12             pAUC_start                    121

13               pAUC_end                    128

14         indivDP_output                      0

15 drug plasma conc. unit                      1

16       is a metabolite?                      0

17           x-axis label Time after dosing (hr)

18           y-axis label     drugX plasma conc.

19         analysis types                      0

20       data file format                      0

21              Tmax_stat                      0

Manual correcting of RDS solved the problem. Thanks alot for your code.

Also at your request: Intel Core i-5 2430M, 8GB RAM, Windows 7 x64, HDD and SSD.

—
Best Regards,
Artem

Complete thread:

Difficulties with run NCA in BEAR Artem Gusev 2017-04-28 11:22 [🇷 for BE/BA]
- Difficulties with run NCA in BEAR yjlee168 2017-04-29 19:47
  - Difficulties with run NCA in BEARArtem Gusev 2017-05-02 09:56
- error fixed in BEAR yjlee168 2017-05-03 19:56
  - error fixed in BEAR Artem Gusev 2017-05-06 07:56
    - bear v2.8.1 released yjlee168 2017-05-06 17:50
      - error with bear v2.8.2 running on R3.4.0 on macos 10.11.6 elcaptin mahmoud-teaima 2017-05-18 18:58
        
        error with bear v2.8.2 running on R3.4.0 on macos 10.11.6 elcaptin yjlee168 2017-05-18 21:48
        
        bear v2.8.2 running on R3.4.0 through RStudio on macos 10.12.5 sierra mahmoud-teaima 2017-05-20 10:32
        
        always on my mind~ yjlee168 2017-05-20 19:43