Bioequivalence and Bioavailability Forum

Dear Helmut!

Thank you for quick response.
I want to clarify one more point. I need to calculate additional parameter in ANOVA - Cohort factor.

Then in the case of a EMA Model Specification is:
sequence+subject(sequence)+period+treatment+cohort
Am I right?

And how Model Specification can be constructed for agencies recommending a mixed-effects model (FDA, Health Canada)?

Thank you!

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Edit: This thread gets less software-related. I opened a new thread for answers. [Helmut]