Bioequivalence and Bioavailability Forum

Relationship between calculated 90% CI and sign. treatment effect in BE [General Statistics]

posted by GM – India, 2017-03-27 21:40 (3378 d 03:06 ago) – Posting: # 17188
Views: 13,706

Dear All,

I have a doubt that, is there any relationship between calculated 90% CI and significant treatment effect in BE studies.

If the 90%CI is one side of hundred, i.e. either (85.00-98.00) or (102.00-119.00) then there should be significant treatment effect. Is this statement correct...?

And why we are generally checking the treatment effect at 5% level of significance...?

Please clarify.

Many thanks in advance.
Regards,
GM.

—
Best Regards,
GM

Complete thread:

Relationship between calculated 90% CI and sign. treatment effect in BEGM 2017-03-27 19:40 [General Statistics]
- 1–2α CI and TOST at α 0.05 Helmut 2017-03-27 23:47
  - 1–2α CI and TOST at α 0.05 GM 2017-03-28 06:50
    - 1–2α CI and TOST at α 0.05 DavidManteigas 2017-03-28 11:48
      - 1–2α CI and TOST at α 0.05 ElMaestro 2017-03-28 13:12
        
        alpha TOST is not alpha 2-sided d_labes 2017-03-28 15:12
        
        Interesting! ElMaestro 2017-03-28 21:10
        
        Google has the answer d_labes 2017-03-29 08:20
        Interesting! DavidManteigas 2017-03-29 11:16
        
        Interesting! ElMaestro 2017-03-29 11:20
        
        Interesting! DavidManteigas 2017-03-29 12:28
        
        95% CI for a test on difference d_labes 2017-03-29 14:24
        Interesting! GM 2017-03-29 20:06
        
        Interesting! nobody 2017-03-30 08:24
      - Relationship between calculated 90% CI and sign. treatment effect in BE GM 2017-03-29 12:11
        
        Relationship between calculated 90% CI and sign. treatment effect in BE DavidManteigas 2017-03-29 12:30

Relationship between calculated 90% CI and sign. treatment effect in BE [General Sta­tis­tics]

Complete thread:

Relationship between calculated 90% CI and sign. treatment effect in BE [General Statistics]