Bioequivalence and Bioavailability Forum • Not estimable in the model

Not estimable in the model [BE/BA News]

posted by ElMaestro – Denmark, 2017-03-14 12:02 (2199 d 13:42 ago) – Posting: # 17152
Views: 21,760

Hi The user,

❝ I decided to continue the topic (moreover Simon kindly directed me here).

❝ Regarding "Not estimable". Could you please share your expirience with following issue? When I use such a model: Sequence+Period+Treatment+Group+Patient(Sequence) I get "Not estimable" in the results of ABE in WNL. Model is wrong? When I delete the "group" than error dissapeares. Comments: it is BE cross over study in 3 groups and all effects are fixed.

Hmmmm... thinking loud here... In a type III model Group will have in your case up to three columns in the model matrix, but every column is equally represented by the subjects in the respective groups. Hence Group has zero df's and no effect for any level of Group can be estimated.

Try a type I model with Group before Subjects, then you'll get something that is estimable, I believe.

—
Pass or fail!
ElMaestro

Complete thread:

EMA BE-GL: Clarifications / Corrections? Helmut 2010-06-22 18:53
- Good news!? d_labes 2010-06-23 10:09
  - Good news!? Helmut 2010-06-23 10:11
    - Update Helmut 2011-02-05 18:48
      - Q&A published 14 March 2011 Helmut 2011-03-16 13:44
        
        Q&A published 14 March 2011 ElMaestro 2011-03-16 14:20
        Phoenix/WinNonlin 6.1.0.173 Helmut 2011-03-17 04:23
        ANOVA party prevails d_labes 2011-03-17 11:00
        
        THX! Helmut 2011-03-19 02:59
        
        Outlier d_labes 2011-03-24 11:55
        
        Outliers - yes, but how? Helmut 2011-03-24 15:09
        
        Questions and Ambiguities d_labes 2011-03-28 14:16
        Residuals and Outliers in Replicate Design Crossover Studies d_labes 2011-04-04 08:53
        
        Info requested ElMag 2011-03-24 12:45
        
        Confused as well... Helmut 2011-03-24 16:50
        
        Q&A published 14 March 2011 Priyanka_S 2011-03-21 14:28
        
        SAS code: Warning d_labes 2011-03-21 16:08
        
        Copy & paste Helmut 2011-03-21 22:38
        
        Subtleties, flaws, questions d_labes 2011-03-22 09:24
        
        Subtleties, flaws, questions Helmut 2011-03-27 20:35
        
        Not estimable in the model The user 2017-03-14 10:16
        
        Not estimable in the modelElMaestro 2017-03-14 11:02
        
        Not estimable in the model The user 2017-03-14 12:13
        
        Not estimable in the model ElMaestro 2017-03-14 12:41
        
        Not estimable in the model Helmut 2017-03-18 21:59
        
        Food not the same between groups Beholder 2021-11-10 14:35
        
        Food not the same between groups ElMaestro 2021-11-17 09:50