## s2wR != mse, FDA != EMA [General Sta­tis­tics]

I like that post, d_labes ,

» But s2wR = MSE is not necessarily true in all cases, although it is in many cases a reasonable assumption.

...and accordingly when the optimizer fails, plugging in the GLM residual (expressed as MSE) as a new starter value for s2wR (and even S2wT where applicable) may be a very decent last-ditch attempt.

» Moreover the FDA evaluation uses intra-subject constrasts to evaluate s2wR

What does this mean? Don't you usually get it from the REML covarance matrix?

I think EMA's approach can be condensed into intra-Subject contrasts to derive S2wR from completers.

Pass or fail!
ElMaestro