Calibration and QC point with same concentration [Bioanalytics]
❝ What happened is I accidentally set up my CC5 concentration the same as MQC (my bad).
That’s not bad at all.
❝ According to my boss, its "common sense" that the conc. shouldn't be same.
I think that the conclusion of the thread (as Steven already noted above) was that an equal concentration of the MQC and one of the CC samples is unlikely but possible.
❝ Total CC points was eight so I think we can reprocess MV data with the problematic point removed and the curve will still have enough CC levels.
Please don’t do that. You will loose information. Citing the EMA’s GL on the calibration curve in BMV:
A relationship which can simply and adequately describe the response of the instrument with regard to the concentration of analyte should be applied.
It is up to you to demonstrate which model (linear, quadratic, …) and weighting scheme fits the data best. See this post (especially the excellent paper by Almeida et al. 2002).❝ Anyway, in my opinion, the CC-QC points do not have to be different, but looks pretty if they are.
1. Yes and 2. Looking pretty is not a scientific category.
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Science Quotes
Complete thread:
- Calibration and QC point with same concentration Ladi 2017-02-23 02:58 [Bioanalytics]
- Calibration and QC point with same concentration Ohlbe 2017-02-23 10:21
- Calibration and QC point with same concentration Relaxation 2017-02-23 15:24
- “Punkteinwaage” Helmut 2017-02-23 15:41
- “Punkteinwaage” Ohlbe 2017-02-23 16:15
- Calibration and QC point with same concentration Ohlbe 2017-02-23 16:20
- Calibration and QC point with same concentration Relaxation 2017-02-23 17:29
- Calibration and QC point with same concentration ElMaestro 2017-02-23 22:02
- Calibration and QC point with same concentration Ladi 2017-02-24 05:50
- Calibration and QC point with same concentration Relaxation 2017-02-24 10:29
- Calibration and QC point with same concentrationHelmut 2017-02-24 12:11
- OT: Beauty of science d_labes 2017-02-24 13:17
- Calibration and QC point with same concentration ElMaestro 2017-02-24 14:05
- Beauty is in the eye of the beholder Helmut 2017-03-03 16:06
- Beauty is in the eye of the beholder ElMaestro 2017-03-03 20:18
- Beauty is in the eye of the beholder Helmut 2017-03-03 16:06
- Calibration and QC point with same concentration Relaxation 2017-02-23 17:29
- “Punkteinwaage” Helmut 2017-02-23 15:41