Bioequivalence and Bioavailability Forum • Calibration and QC point with same concentration

Calibration and QC point with same concentration [Bioanalytics]

posted by Relaxation – Germany, 2017-02-23 16:24 (3051 d 18:24 ago) – Posting: # 17099
Views: 12,080

❝ Dear All,

❝

❝ I was wondering if concentration of a calibration point can be equal to a QC point?

»...

❝ Do guidelines allow that or is just common sense that they should be different?

And a "Dear All" from me, too.
I am also not aware of any guideline giving a requirement that there should be different concentrations.
As this is not what I observed in most trials I was involved in and I had not heard of such a rule at all until today, I think I might learn something new here.

So my follow-up question:
is there really any rule, that CC and QC concentrations have to differ at all? And why would it be common sense, that they should be different, as long as I do not use the same stock solution?
I just can't see a reason (but I am also by no means a bioanalyst).

Best regards,

Steven.

Complete thread:

Calibration and QC point with same concentration Ladi 2017-02-23 02:58 [Bioanalytics]
- Calibration and QC point with same concentration Ohlbe 2017-02-23 10:21
- Calibration and QC point with same concentrationRelaxation 2017-02-23 15:24
  - “Punkteinwaage” Helmut 2017-02-23 15:41
    - “Punkteinwaage” Ohlbe 2017-02-23 16:15
  - Calibration and QC point with same concentration Ohlbe 2017-02-23 16:20
    - Calibration and QC point with same concentration Relaxation 2017-02-23 17:29
      - Calibration and QC point with same concentration ElMaestro 2017-02-23 22:02
      - Calibration and QC point with same concentration Ladi 2017-02-24 05:50
        
        Calibration and QC point with same concentration Relaxation 2017-02-24 10:29
        Calibration and QC point with same concentration Helmut 2017-02-24 12:11
        
        OT: Beauty of science d_labes 2017-02-24 13:17
        Calibration and QC point with same concentration ElMaestro 2017-02-24 14:05
        
        Beauty is in the eye of the beholder Helmut 2017-03-03 16:06
        
        Beauty is in the eye of the beholder ElMaestro 2017-03-03 20:18