Alternative CI for BE decision [Power / Sample Size]

posted by Helmut Homepage – Vienna, Austria, 2017-02-09 13:41 (1531 d 13:12 ago) – Posting: # 17045
Views: 21,068

Hi ElMaestro,

» If someone reports a CI of 0.8456-1.0000 to me, then it might in actuality imply a 90% CI of 0.8456-0.98765 or whatever. Is that science?

As zizou noted above it is less informative than the conventional (shortest) CI – we only know that the GMR is <1 – and we can’t calculate the CV from the CI any more.

» Why not just go all the way and adjust all CI's so that they span across 1.0 like...what was his name... some statistician twenty-thirty years ago.... his name was Lester Hamsterballs or something...?

41 years ago. Westlake. Wilfred J. Westlake.

Took me ages to persuade Pharsight/Certara to remove it from the standard output of WinNonlin (available till v6.3).

Dif-tor heh smusma 🖖
Helmut Schütz
[image]

The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes

Complete thread:

Activity
 Admin contact
21,419 posts in 4,475 threads, 1,510 registered users;
online 8 (0 registered, 8 guests [including 3 identified bots]).
Forum time: Wednesday 03:54 CEST (Europe/Vienna)

In the Middles Ages the lingua franca of science was Latin.
Nowadays the language of science is bad English.    Anonymous

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5