Bioequivalence and Bioavailability Forum • The formula of a CI for TRR|RTR|RRT

The formula of a CI for TRR|RTR|RRT [RSABE / ABEL]

posted by Mahmoud – Jordan, 2017-01-19 08:01 (2985 d 06:56 ago) – Posting: # 16977
Views: 10,775

❝ What formula is used for calculation of a confidence interval of a difference of test and reference pharmaceuticals for three sequences (TRR|RTR|RRT)?

Dear Sir

Lower= EXP(Mean(T)-Mean(R)-SQRT(var(intra)*1/6(1/n1+1/n2+1/n3)))

Upper= EXP(Mean(T)-Mean(R)+ SQRT(var(intra)*1/6(1/n1+1/n2+1/n3)))

Mahmoud Abdel-Mohsen Ph.D

Edit: Full quote removed. Please delete everything from the text of the original poster which is not necessary in understanding your answer; see also this post #5! [Helmut]

Complete thread:

The formula of a CI for TRR|RTR|RRT Yura 2017-01-17 09:30 [RSABE / ABEL]
- The formula of a CI for TRR|RTR|RRT BE-proff 2017-01-17 12:33
  - The formula of a CI for TRR|RTR|RRT Yura 2017-01-17 14:13
  - Geometric, Arithmetic, Harmonic, Disharmonic … d_labes 2017-01-18 14:36
- The formula of a CI for TRR|RTR|RRT d_labes 2017-01-18 14:30
  - The formula of a CI for TRR|RTR|RRT Yura 2017-01-19 05:43
- The formula of a CI for TRR|RTR|RRTMahmoud 2017-01-19 07:01
  - The formula of a CI for TRR|RTR|RRT Yura 2017-01-19 08:16
    - The formula of a CI for TRR|RTR|RRT Mahmoud 2017-01-19 08:55
      - The formula of a CI for TRR|RTR|RRT Yura 2017-01-20 06:28
        
        The formula of a CI for TRR|RTR|RRT Mahmoud 2017-01-20 09:11
        
        The formula of a CI for TRR|RTR|RRT Yura 2017-01-20 11:33