Antiemetic Drugs can change PK profiles [PK / PD]

posted by mittyri – Russia, 2016-12-27 18:15 (2968 d 10:14 ago) – Posting: # 16887
Views: 5,601

Dear anky1212,

This question is not so easy to answer.
The best way to control vomiting and nausea is peripheral dopamine receptor blocker like Domperidone or central blocker like Metoclopramide (also blocks central effects, but they aren't needed here, right?).
By the way using these drugs you can change gastric/enteric motility and also bioavailability of drugs of interest.
Please consider to review this paper
I didn't find any data regarding active antiemetic therapy in BEQ studies for Stalevo.

Maybe more experienced colleagues have more information...

Kind regards,
Mittyri

Complete thread:

UA Flag
Activity
 Admin contact
23,380 posts in 4,914 threads, 1,662 registered users;
34 visitors (0 registered, 34 guests [including 13 identified bots]).
Forum time: 04:30 CET (Europe/Vienna)

Skill is a function of chance.
It’s an intuitive best-use of chance situations.    Philip K. Dick

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5