CI and alfa [RSABE / ABEL]
Hello Yura,
Something sounds a bit odd here. TRR/RTR/RRT with two different Ref's is not a replicate design; alpha adjustment is in that situation usually not what you want to do. But I would be entirely wrong, depending on the question you are actually asking in your trial. What is the purpose of the R1-R2 CI?
Let's get some more info.
❝ We spend in replicate design TRR / RTR / RRT three repeated measurements. Question: how to take the level of alpha and confidence interval for the point estimate calculation between measurements (T-R1, T-R2, R1-R2)? I assumed an alpha of 0.017 and CI 96.6.
Something sounds a bit odd here. TRR/RTR/RRT with two different Ref's is not a replicate design; alpha adjustment is in that situation usually not what you want to do. But I would be entirely wrong, depending on the question you are actually asking in your trial. What is the purpose of the R1-R2 CI?
Let's get some more info.

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Pass or fail!
ElMaestro
Pass or fail!
ElMaestro
Complete thread:
- CI and alfa Yura 2016-11-23 08:50 [RSABE / ABEL]
- CI and alfaElMaestro 2016-11-24 21:35
- CI and alfa Yura 2016-11-25 07:51
- iteratively adjusted α Helmut 2016-11-25 13:00
- iteratively adjusted α Yura 2016-11-25 19:28
- iteratively adjusted α Helmut 2016-11-25 13:00
- CI and alfa Yura 2016-11-25 07:51
- CI and alfaElMaestro 2016-11-24 21:35