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Registerextra-reference design [Design Issues]
posted by Helmut 
– Vienna, Austria, 2016-11-10 14:28 (2722 d 20:42 ago) – Posting: # 16795
Views: 5,626
Hi Yura,
May I ask: Which presentation?
α 0.1 was suggested in the past because of the low power of the test (between subjects). But:
❝ There was information in presentation …
May I ask: Which presentation?
❝ … about higt importance of sequence effect and toughening of level of its significance up to 0,1 (instead of 0,05) i. e. the effect of the period can be ignored
α 0.1 was suggested in the past because of the low power of the test (between subjects). But:
- Testing for a sequence effect (or better: unequal carry-over) is flawed and should be abandoned (see this post and references).
- Testing for a period effect is futile as well. A period effect means out in cross-over studies (unless sequences are extremely (‼) unbalanced). As Detlew wrote above, a true period effect may give a biased treatment estimate in the extra-reference design. Therefore, it should not be used.
—
Dif-tor heh smusma 🖖🏼 Довге життя Україна!![[image]](https://static.bebac.at/pics/Blue_and_yellow_ribbon_UA.png)
Helmut Schütz
![[image]](https://static.bebac.at/img/CC by.png)
The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes
Dif-tor heh smusma 🖖🏼 Довге життя Україна!
Helmut Schütz
The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes
Complete thread:
- Design HVDP Yura 2016-11-09 09:10 [Design Issues]
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- extra-reference design d_labes 2016-11-09 12:01
- extra-reference design Yura 2016-11-10 12:18
- extra-reference designHelmut 2016-11-10 13:28
- extra-reference design Yura 2016-11-10 13:49
- extra-reference designHelmut 2016-11-10 13:28
- extra-reference design Yura 2016-11-10 12:18
- Design HVDP mittyri 2016-11-09 12:13
- extra-reference design d_labes 2016-11-09 12:01
Ing. Helmut Schütz