Still SF [Two-Stage / GS Designs]

posted by VStus – Poland, 2016-10-11 09:10 (2083 d 07:27 ago) – Posting: # 16716
Views: 11,714

Hi Helmut,

» lucid words about SF and great ideas about hacking embeded Linux-machines. :-D

Well, it's a proven solution (not by me!), just not quite legal in most of civilized countries ;)

» In a TSD we have some chances to demonstrate BE already in the first stage. Hence, my personal recommendation for n1 75-80% of the fixed sample’s n.

After playing with data from other studies, I've made a suggestion that same recommendation is good single stage cross-over with 2 groups to keep the study safe or "conservative"... We can then demonstrate BE based on larger (first) group if requested by regulators.

Regards, VStus

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