Vss: MIT is needed anyway... [PK / PD]

posted by mittyri – Russia, 2016-09-24 02:38 (2557 d 02:52 ago) – Posting: # 16669
Views: 16,429

Hi ElMaestro,

❝ We don't have to be sheep, right?


Certainly not.
But as Detlew wisely noted, we need to know MIT

I would cite another good article1
[image]

The equation for FO input is the same as given by Detlew, just another names:
[image]

So without tlag and ka you cannot calculate Vss, sorry

1. Watari, N. & Benet, L.Z. Journal of Pharmacokinetics and Biopharmaceutics (1989) 17: 593. doi:10.1007/BF01071351

Kind regards,
Mittyri

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