old bear and friends [🇷 for BE/BA]

posted by yjlee168 Homepage – Kaohsiung, Taiwan, 2016-09-16 11:42 (2750 d 23:27 ago) – Posting: # 16647
Views: 12,842

(edited by yjlee168 on 2016-09-16 18:00)

Dear xtianbadillo,

I wonder that you are using the previous version of bear. I have already fixed the error since v2.7.1. Now it's v2.7.7.

The error comes from that the data point selection method (such as ARS) fails to select at least three data points after Cmax to estimate λz. Thus, there is no drug plasma conc. (i.e., 'y') selected at all. That's what the error messages tell us. In other words, you may have at least one subject who had insufficient data points (≧ 3 data points after Cmax) to estimate λz. May I know what version of bear you used? You can upgrade bear from Sourceforge if you like (not on CRAN any more; very sorry about that). And try it again with the same dataset using ARS or others. It will tell you which subjects get involved with insufficient data points.

Hope this can help.

❝ ...I changed the default settings as you said and the issue was solved.


All the best,
-- Yung-jin Lee
bear v2.9.1:- created by Hsin-ya Lee & Yung-jin Lee
Kaohsiung, Taiwan https://www.pkpd168.com/bear
Download link (updated) -> here

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