Bioequivalence and Bioavailability Forum • Significance of UL/LL in sample size calculation

Significance of UL/LL in sample size calculation [Power / Sample Size]

posted by ElMaestro – Denmark, 2016-08-30 16:07 (3128 d 21:27 ago) – Posting: # 16615
Views: 5,788

Hi BE-proff,

❝ Do you have an example of code for PowerTOST to plot a curve for power assessment?

Something like this for a 222BE study:

GetMeTheCurve=function(CV, GMR)

{

 N=2*c(5:40)

 Pwr=N

 for (i in 1:length(N))

 {

  Pwr[i]=power.TOST(n=N[i], CV=CV, theta0=GMR)

 }

 ##

 plot(N, Pwr)

 return(0)

}



GetMeTheCurve(CV=0.28, GMR=0.95)

—
Pass or fail!
ElMaestro

Complete thread:

Significance of UL/LL in sample size calculation BE-proff 2016-08-30 08:35 [Power / Sample Size]
- Significance of UL/LL in sample size calculation ElMaestro 2016-08-30 09:04
  - Significance of UL/LL in sample size calculation BE-proff 2016-08-30 13:53
    - Significance of UL/LL in sample size calculationElMaestro 2016-08-30 14:07
      - a very nice function of powerTOST mittyri 2016-08-30 14:25
        
        nice functions of powerTOST d_labes 2016-08-30 16:39